abstract：BACKGROUND:Hepatitis B virus (HBV) is a hepatotropic DNA virus, and its DNA may be a potent inflammatory molecule. Interferon-inducible protein 16 (IFI16), a newly discovered DNA sensor, plays an important role in the process of inflammation in viral infections. Our study sought to identify a correlation between IFI16 ...

journal_title：BMC gastroenterology

authors： Pang X,Li X,Mo Z,Huang J,Deng H,Lei Z,Zheng X,Feng Z,Xie D,Gao Z

更新日期：2018-05-09 00:00:00

abstract：BACKGROUND:In a recent study we had evidence that sulphite oxidase (SO) may be a relevant autoantigen in primary sclerosing cholangitis (PSC). Aim of the present study was, therefore, to analyse humoral and cellular immune-reactivity towards SO in these patients in more detail. METHODS:Sera from 53 patients with PSC (...

journal_title：BMC gastroenterology

authors： Preuß BE,Berg CP,Werner C,Plankenhorn S,Malek NP,Klein R

更新日期：2018-05-02 00:00:00

abstract：BACKGROUND:Pancreatic duct disruption is a challenging condition leading to pancreatic juice leakage and consequently to pancreatic fluid collections. The manifestations of pancreatic main duct leak include pseudocysts, walled-off necrosis, pancreatic fistulas, ascites, pleural and pericardial effusions. Pseudocyst for...

journal_title：BMC gastroenterology

authors： Gerosa M,Chiarelli M,Guttadauro A,De Simone M,Tagliabue F,Costa M,Terragni S,Cioffi U

更新日期：2018-04-23 00:00:00

abstract：BACKGROUND:Bleeding after endoscopic submucosal dissection (ESD) in antithrombotic drug users is still one of the important issues to be solved. We performed scheduled second-look endoscopy (SLE) 5 days after ESD, when the resumption of antithrombotic agents is assumed to have achieved a steady state, rather than on th...

journal_title：BMC gastroenterology

authors： Izumikawa K,Iwamuro M,Inaba T,Ishikawa S,Kuwaki K,Sakakihara I,Yamamoto K,Takahashi S,Tanaka S,Wato M,Okada H

更新日期：2018-04-10 00:00:00

abstract：BACKGROUND:Perianal fistula surgery can damage the anal sphincters which may cause faecal incontinence. By measuring regional pressures, 3D-HRAM potentially provides better guidance for surgical strategy in patients with perianal fistulas. The aim was to measure regional anal pressures with 3D-HRAM and to compare these...

journal_title：BMC gastroenterology

authors： Felt-Bersma RJF,Vlietstra MS,Vollebregt PF,Han-Geurts IJM,Rempe-Sorm V,Vander Mijnsbrugge GJH,Molenaar CBH

更新日期：2018-04-04 00:00:00

abstract：BACKGROUND:Anal residual tumors are consensually identified within six months of chemoradiotherapy and represent a persistent lesion that may have prognostic value for overall survival. The aim of this study was to evaluate the association of HPV and HIV status, p16 expression level and TP53 mutations with the absence ...

journal_title：BMC gastroenterology

authors： Soares PC,Abdelhay ES,Thuler LCS,Soares BM,Demachki S,Ferro GVR,Assumpção PP,Lamarão LM,Ribeiro Pinto LF,Burbano RMR

更新日期：2018-02-21 00:00:00

abstract：BACKGROUND:The gastric microbiota has recently been implicated in the causation of organic/structural gastroduodenal diseases (gastric and duodenal ulcers, gastric cancer) in patients with Helicobacter pylori (H. pylori) infection. We aimed to ascertain, in patients harbouring H. pylori, the role of the gastric microbi...

journal_title：BMC gastroenterology

authors： Pereira V,Abraham P,Nallapeta S,Shetty A

更新日期：2018-01-26 00:00:00

abstract：BACKGROUND:Extramedullary plasmacytoma is a very rare tumor derived from plasma cells and found outside the bone marrow. Most have been identified in patients with the more aggressive anaplastic form of the disease. Only a few cases of primary pancreatic plasmacytoma have been reported. CASE PRESENTATION:We present a ...

journal_title：BMC gastroenterology

authors： Lu T,Pu H,Zhao G

更新日期：2017-12-20 00:00:00

abstract：BACKGROUND:Familial adenomatous polyposis (FAP) is a rare, autosomal dominant disease clinically characterized by the early onset of many adenomatous polyps throughout the colon, which turn into colon cancer, if left untreated. In FAP patients, polyps can also occur in the upper gastrointestinal (GI) tract, especially ...

journal_title：BMC gastroenterology

authors： Purchiaroni F,Nakajima T,Sakamoto T,Abe S,Saito Y

更新日期：2017-12-08 00:00:00

abstract：BACKGROUND:The current clinical practice on chronic hepatitis B (CHB) requires better on-treatment monitoring of viral persistence. Quantified assays for hepatitis B surface antigen (HBsAg) and core-related antigen (HBcrAg) hold promise for further optimization of therapy. Here, we aimed to characterize HBcrAg during t...

journal_title：BMC gastroenterology

authors： Zhang ZQ,Zhang XN,Lu W,Wang YB,Weng QC,Feng YL

更新日期：2017-12-04 00:00:00

abstract：BACKGROUND:Stercoral colitis is a rare inflammatory process involving the colonic wall secondary to fecal impaction with high morbidity and mortality; especially if complicated with ischemic colitis, stercoral ulcer formation and subsequent perforation. There are several case reports published on abdominal perforation ...

journal_title：BMC gastroenterology

authors： Naseer M,Gandhi J,Chams N,Kulairi Z

更新日期：2017-11-28 00:00:00

abstract：BACKGROUND:Approximately 60% of patients presenting to dentists with erosive tooth wear have significant gastroesophageal reflux (GERD), despite minor reflux symptoms. No longitudinal studies of reflux-associated erosive tooth wear and of reflux characteristics have been reported to date. The aim of this study was to c...

journal_title：BMC gastroenterology

authors： Wilder-Smith CH,Materna A,Martig L,Lussi A

更新日期：2017-10-25 00:00:00

abstract：BACKGROUND:Occurrence of metastatic cancer to the stomach is rare, particularly in patients with prostate cancer. Gastric metastasis generally presents as a solitary and submucosal lesion with a central depression. CASE PRESENTATION:We describe a case of gastric metastasis arising from prostate cancer, which is almost...

journal_title：BMC gastroenterology

authors： Inagaki C,Suzuki T,Kitagawa Y,Hara T,Yamaguchi T

更新日期：2017-08-07 00:00:00

abstract：BACKGROUND:By means of 24 h multi-channel intraluminal impedance and pH recording (MII/pH), patients with heartburn and normal upper gastrointestinal endoscopy findings can be classified into those with non-erosive reflux disease (NERD) and those with reflux hypersensitivity (RH). Therefore, in this study, we investiga...

journal_title：BMC gastroenterology

authors： Gao F,Gao Y,Chen X,Qian J,Zhang J

更新日期：2017-05-23 00:00:00

abstract：BACKGROUND:The evidence on the role of gut microbiota in post-infectious irritable bowel syndrome (PI-IBS) is convincing. Lactobacillus spp. positively affect IBS symptoms, although the mechanisms through which probiotics exert their beneficial effects are largely unknown. The aim of the study is to evaluate the role o...

journal_title：BMC gastroenterology

authors： Compare D,Rocco A,Coccoli P,Angrisani D,Sgamato C,Iovine B,Salvatore U,Nardone G

更新日期：2017-04-14 00:00:00

abstract：BACKGROUND:Efficacy of maintenance therapy in ulcerative colitis (UC) in the remission stage has been reported to depend on release profile or dosing regimen of oral 5-aminosalicylic acid (5-ASA) products used. Aim of this study is to investigate real life results in using oral 5-ASA products for maintaining mild to mo...

journal_title：BMC gastroenterology

authors： Nagahori M,Kochi S,Hanai H,Yamamoto T,Nakamura S,Omuro S,Watanabe M,Hibi T,OPTIMUM Study Group.

更新日期：2017-04-04 00:00:00

abstract：BACKGROUND:Gastrointestinal fistula (GIF) in severe acute pancreatitis (SAP) is considered as a sparse episode and studied sporadically in the literature. There is paucity of data on the prediction of the effect on risk of GIF in patient with SAP. This study was aimed to investigate risk factors related to GIF in the d...

journal_title：BMC gastroenterology

authors： Hua Z,Su Y,Huang X,Zhang K,Yin Z,Wang X,Liu P

更新日期：2017-02-14 00:00:00

abstract：BACKGROUND:Little is known about the prognostic impact of cirrhosis on long-term survival of patients with combined hepatocellular-cholangiocarcinoma (cHCC-CC) after hepatic resection. The aim of this study was to elucidate the long-term outcome of hepatectomy in cHCC-CC patients with cirrhosis. METHODS:A total of 144...

journal_title：BMC gastroenterology

authors： Zhou YM,Sui CJ,Zhang XF,Li B,Yang JM

更新日期：2017-02-10 00:00:00

abstract：BACKGROUND:We assessed how the diagnosis of Celiac Disease (CD) is made and how the new ESPGHAN guidelines can be applied in children from countries with different resources. METHODS:A real life prospective study was performed in 14 centres of 13 different Mediterranean countries. Participants were asked to apply the ...

journal_title：BMC gastroenterology

authors： Smarrazzo A,Misak Z,Costa S,Mičetić-Turk D,Abu-Zekry M,Kansu A,Abkari A,Bouziane-Nedjadi K,Ben Hariz M,Roma E,Velmishi V,Legarda Tamara M,Attard T,Djurisic V,Greco L,Magazzù G

更新日期：2017-01-21 00:00:00

abstract：BACKGROUND:Liver injury and regeneration involve complicated processes and are affected by various physio-pathological conditions. Surgically, severe liver injury after surgical resection often leads to fatal liver failure, especially with some underlying pathological conditions such as steatosis. Therefore, protection...

journal_title：BMC gastroenterology

authors： Haga S,Yimin,Ozaki M

更新日期：2017-01-13 00:00:00

abstract：BACKGROUND:Faecal calprotectin (FC) is one of the most widely used non-invasive tests for the diagnosis and assessment of Crohn's disease (CD) activity. Despite this, factors other than disease activity which affect levels have not been extensively reviewed. This is of importance when using FC in the diagnostic setting...

journal_title：BMC gastroenterology

authors： Mendall MA,Chan D,Patel R,Kumar D

更新日期：2016-10-07 00:00:00

abstract：BACKGROUND:Gastric diseases are a worldwide problem in modern society, as reported in the USA, in the range of 0.5-2 episodes/year/person and an incidence of 5-100 episodes/1000/week according to seasons and age. There is convincing evidence that oxidative stress is involved in the pathogenesis of acute gastric injury....

journal_title：BMC gastroenterology

authors： Uberti F,Bardelli C,Morsanuto V,Ghirlanda S,Molinari C

更新日期：2016-10-07 00:00:00

abstract：BACKGROUND:Perforation of the colon occurring during or shortly following colonoscopy or barium enema is a rare complication of collagenous colitis (CC). "Spontaneous" perforation in CC, in which no instigating factor is identified, is even less common, with only five cases reported to date. We report herein an additio...

journal_title：BMC gastroenterology

authors： Mitchell A,Dugas A

更新日期：2016-10-06 00:00:00

abstract：BACKGROUND:Gastroparesis (Gp) is a poorly understood chronic gastrointestinal medical condition for which patient reported outcomes (PRO) are lacking. Previously developed symptoms scoring has been used for several decades. Using symptoms scores as a basis for documentation, 12 years of support/focus group patient feed...

journal_title：BMC gastroenterology

authors： Cutts T,Holmes S,Kedar A,Beatty K,K Mohammad M,Abell T

更新日期：2016-08-31 00:00:00

abstract：BACKGROUND:The <80 % Helicobacter pylori eradication rate with sequential therapy is unsatisfactory. Modified bismuth quadruple therapy, replacing metronidazole with amoxicillin, could be promising because H. pylori resistance to tetracycline or to amoxicillin is relatively low. A 14-day modified bismuth quadruple prot...

journal_title：BMC gastroenterology

authors： Lee JY,Kim N,Park KS,Kim HJ,Park SM,Baik GH,Shim KN,Oh JH,Choi SC,Kim SE,Kim WH,Park SY,Kim GH,Lee BE,Jo Y,Hong SJ

更新日期：2016-07-26 00:00:00

abstract：BACKGROUND:Rebamipide is a gastroprotective agent with promising results against gastric damage induced by non-steroidal anti-inflammatory drugs. The present study evaluated if rebamipide protects against naproxen-induced gastric damage in healthy volunteers. Changes in gastric PGE2 tissue concentration were also evalu...

journal_title：BMC gastroenterology

authors： Gagliano-Jucá T,Moreno RA,Zaminelli T,Napolitano M,Magalhães AF,Carvalhaes A,Trevisan MS,Wallace JL,De Nucci G

更新日期：2016-06-04 00:00:00

abstract：BACKGROUND:Transarterial chemoembolization (TACE) and sorafenib are the therapeutic standard for intermediate and advanced stage hepatocellular carcinoma (HCC) patients respectively. High costs with adverse events (AE) of sorafenib might limit sorafenib dosage, further affecting therapeutic response. To attain greatest...

journal_title：BMC gastroenterology

authors： Hsiao WD,Peng CY,Chuang PH,Lai HC,Cheng KS,Chou JW,Chen YY,Yu CJ,Feng CL,Su WP,Chen SH,Kao JT

更新日期：2016-04-27 00:00:00

abstract：BACKGROUND:Polyethylene glycol is commonly used to manage constipation and is available with or without electrolytes. The addition of electrolytes dates back to its initial development as lavage solutions in preparation for gastrointestinal interventions. The clinical utility of the addition of electrolytes to polyethy...

journal_title：BMC gastroenterology

authors： Katelaris P,Naganathan V,Liu K,Krassas G,Gullotta J

更新日期：2016-03-31 00:00:00

abstract：BACKGROUND:Carrageenan is a traditional ingredient that has been widely used in the food industry. In the present study, we propose a hypothesis that carrageenan is a conditional inflammatory agent. When the intestinal tract is in an "unhealthy" state such as that during bacterial infection or acute inflammation, carra...

journal_title：BMC gastroenterology

authors： Wu W,Wang F,Gao X,Niu T,Zhu X,Yan X,Chen H

更新日期：2016-03-25 00:00:00

abstract：BACKGROUND:Approximately 0.2-1 % of children suffers from abdominal migraine (AM). Pathophysiology of AM has not been adequately studied. This study evaluated gastric motility in children with AM. METHODS:Seventeen children (6 boys), within an age range of 4-15 years, referred to a tertiary care paediatric unit, North...

journal_title：BMC gastroenterology

authors： Devanarayana NM,Rajindrajith S,Benninga MA

更新日期：2016-02-29 00:00:00

abstract：BACKGROUND:Approximately 2.7 million Americans are chronically infected with hepatitis C virus (HCV). HCV patients with cirrhosis form the largest group of persons at high risk for hepatocellular carcinoma (HCC). Increased oxidative stress is regarded as a major mechanism of HCV-related liver disease progression. Defic...

journal_title：BMC gastroenterology

authors： Kataria Y,Deaton RJ,Enk E,Jin M,Petrauskaite M,Dong L,Goldenberg JR,Cotler SJ,Jensen DM,van Breemen RB,Gann PH

更新日期：2016-02-29 00:00:00

abstract：BACKGROUND:Pancreatic hamartoma is an extremely rare benign disease of the pancreas. Only 30 cases have been reported to date. CASE PRESENTATION:A 68-year-old man presented with an asymptomatic solid and multi-cystic lesion in the uncus of the pancreas, incidentally detected on abdominal enhanced computed tomography. ...

journal_title：BMC gastroenterology

authors： Matsushita D,Kurahara H,Mataki Y,Maemura K,Higashi M,Iino S,Sakoda M,Shinchi H,Ueno S,Natsugoe S

更新日期：2016-01-14 00:00:00

abstract：BACKGROUND:In China, the incidence of Inflammatory bowel disease (IBD) has shown a significant growth trend. Analysis of the epidemiology, clinical manifestations, diagnostic means, and treatment of IBD will further improve the clinician's understanding of IBD, improve knowledge and further enable early diagnosis and s...

journal_title：BMC gastroenterology

authors： Zhai H,Liu A,Huang W,Liu X,Feng S,Wu J,Yao Y,Wang C,Li Q,Hao Q,Hu J,Zhang S

更新日期：2016-01-12 00:00:00

abstract：BACKGROUND:Distal diminutive colorectal polyps are common and accurate endoscopic prediction of hyperplastic or adenomatous polyp histology could reduce procedural time, costs and potential risks associated with the resection. Within this study we assessed whether digital chromoendoscopy can accurately predict the hist...

journal_title：BMC gastroenterology

authors： Rath T,Tontini GE,Nägel A,Vieth M,Zopf S,Günther C,Hoffman A,Neurath MF,Neumann H

更新日期：2015-10-22 00:00:00

abstract：BACKGROUND:Coeliac disease is characterised by villous atrophy, which usually normalises after gluten withdrawal. Sometimes the revaluation of duodenal histology is required during follow-up, even if the methodology for comparing duodenal histology before and after introducing a gluten-free diet is not yet established....

journal_title：BMC gastroenterology

authors： Elli L,Zini E,Tomba C,Bardella MT,Bosari S,Conte D,Runza L,Roncoroni L,Ferrero S

更新日期：2015-10-14 00:00:00

abstract：BACKGROUND:To exam the biochemical, obstetric management and pregnancy outcome in women with intrahepatic cholestasis of pregnancy (ICP) and treatment with ursodeoxycholic acid (UDCA). METHODS:Pregnancy outcome in patients with ICP (N = 307) was studied and patients treated with UDCA (N = 208) vs. no UDCA were compare...

journal_title：BMC gastroenterology

authors： Joutsiniemi T,Timonen S,Linden M,Suvitie P,Ekblad U

更新日期：2015-07-29 00:00:00

abstract：BACKGROUND:Autoimmune hepatitis causes chronic hepatitis and often leads to cirrhosis and death without treatment. We wanted to see if having access to primary care or insurance prior to diagnosis is associated with better outcomes for patients in an urban, public hospital with mostly socioeconomically disadvantaged Hi...

journal_title：BMC gastroenterology

authors： Kim D,Eshtiaghpour D,Alpern J,Datta A,Eysselein VE,Yee HF

更新日期：2015-07-28 00:00:00

abstract：BACKGROUND:Studies concerning clinical course and outcome of acute pancreatitis (AP) according to etiologies were rare, especially after year 2000. This study was designed to investigate the difference between the clinical course of alcoholic and biliary AP. METHODS:Of the 153 patients diagnosed as AP with a first att...

journal_title：BMC gastroenterology

authors： Cho JH,Kim TN,Kim SB

更新日期：2015-07-25 00:00:00

abstract：BACKGROUND:Signet ring cell carcinoma of the colon and rectum is rare, and most cases are detected at an advanced stage. We present a case of primary signet ring cell carcinoma detected at an early stage by magnifying endoscopy with narrow-band imaging (NBI) and crystal violet staining. CASE PRESENTATION:A 73-year-old...

journal_title：BMC gastroenterology

authors： Ohnita K,Isomoto H,Akashi T,Hashiguchi K,Matsushima K,Minami H,Akazawa Y,Yamaguchi N,Takeshima F,To K,Takeshita H,Yasui H,Abe K,Nakao K

更新日期：2015-07-24 00:00:00

abstract：BACKGROUND:Desmoid tumors are a group of benign, invasive, solid tumors that are relatively rare in the general population, but can occur in up to 21 % of patients with Familial Adenomatous Polyposis (FAP). They can be difficult to treat and have high rates of recurrence even after resection. Our goal with this study w...

journal_title：BMC gastroenterology

authors： Slowik V,Attard T,Dai H,Shah R,Septer S

更新日期：2015-07-16 00:00:00